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Adherence news

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Adherence
Australians find that money problems lead to poorer adherence to HIV therapy

Difficulties meeting pharmacy costs and those incurred travelling for clinic appointments are associated with interrupting or stopping HIV therapy, Australian investigators report in HIV Medicine. Overall, 14%

Published
13 August 2012
By
Michael Carter
Adherence
Digital pills make their way to market

Digestible microchips embedded in drugs may soon tell doctors whether a patient is taking their medications as prescribed.

Published
02 August 2012
From
Nature
Delivery of care
Community-based support aids retention, adherence and treatment response

Patient retention and linkage throughout the cascade of HIV care remains very low, placing the concept of ‘test and treat’ as part of the solution to ending

Published
26 July 2012
By
Lesley Odendal
Changing treatment
Second-line HIV therapy effective and durable in South Africa, and adherence support could improve rates of viral suppression

Second-line antiretroviral therapy in South Africa achieves durable viral suppression in three-quarters of patients and is associated with an increase in CD4 cell count, investigators report in

Published
27 June 2012
By
Michael Carter
Injecting drug users
Active injecting drug users must be provided with adherence support when they start HIV therapy

Chances of achieving an undetectable viral load are equally poor for patients who inject heroin, cocaine, or a combination of these two drugs, Canadian researchers report in

Published
20 June 2012
By
Michael Carter
Adherence
HIV-Positive Drinkers Choose Alcohol Over ART

Half of HIV-positive drinkers receiving antiretroviral therapy (ART) intentionally skipped or stopped taking their medications when they consumed alcohol, in the mistaken belief that combining ART drugs and alcohol is somehow toxic, according to a prospective cohort study.

Published
12 June 2012
From
Medscape (requires free registration)
PrEP
Adherence Challenges in Intermittent HIV PrEP Study

Intermittent use of Truvada (tenofovir plus emtricitabine) as pre-exposure prophylaxis was associated with poor adherence, compared with daily use of the tablet to prevent HIV infection, according to results of a small clinical trial published in the online scientific journal PLoS ONE.

Published
30 May 2012
From
AIDSMeds
PrEP
Study Reports Data on the Use of Intermittent ARV-Based Pre-Exposure Prophylaxis for HIV Prevention

A Phase I clinical trial comparing a daily regimen of antiretroviral pre-exposure prophylaxis (PrEP) with an intermittent regimen found that rates of adherence to intermittent dosing regimens were lower than adherence to daily dosing. The study is the first ever to report data on intermittent antiretroviral PrEP use in humans.

Published
28 May 2012
From
IAVI press release
Adherence
HIV treatment breaks lead to drug resistance in the female genital tract

Antiretroviral treatment interruptions of 48 hours or more are associated with the emergence of resistant strains of HIV in the female genital tract, investigators report in the

Published
24 May 2012
By
Michael Carter
Adherence
Canadian cohort shows viral suppression most likely with atazanavir/ritonavir-based HIV treatment after 6 months

Antiretroviral therapy based on the ritonavir-boosted protease inhibitor atazanavir (Reyataz) was more likely to achieve virological suppression after six months than treatment containing the non-nucleoside reverse transcriptase inhibitor

Published
11 May 2012
By
Michael Carter
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